Thursday, April 27, 2006

Apomorphine: Drug of Mystery?

Apomorphine is an old drug, dating at least back to the 1860s. It has found many uses, including as a treatment for Parkinson's Disease, and a treatment for Erectile Dysfunction. Apomorphine is also an efficient emetic at proper doses. In the context of life extension and longevity, apomorphine has proven to be a good trigger for HGH release. Apomorphine is not an opiate analgesic like morphine, and is not addictive.

I suspect that apomorphine will find many more uses, given its multiple potencies. A good sex life is important for a satisfying life, whatever its length, and apomorphine not only induces penile erection, it also is a dopamine agonist, which suggests that the sex drive itself would be stimulated by apomorphine, and the sex act made more pleasurable.

Given the emetic properties of higher doses of apomorphine, it is not likely to become a drug of abuse. And given the several decades since its initial use in humans, the more lethal and disabling side effects of a drug would have been found. In other words, we have a drug, apomorphine, that likely has a positive effect on longevity via HGH release, and a positive effect on sexual desire, performance, and pleasure. Yet very few people have heard of apomorphine.

One more thing: apomorphine has been found to be protective of mitochondria in the central nervous system. Consider the implications of that.



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